Im looking for advice on Estrogen inhibitors on testosterone cycle.

[hecarim]

My questions: Which should I consider? Anastrozole maybe?
How you use it (dosage and when)?
And Side effects to be known.....

 

[SalvatoreCorvus]

Hello.

What are the e2 blood test values? What dose of testosterone are you using?

 

[hecarim]

Last cycle I was on 300mg Enanthate weekly and e2 side effects (sensitive nipples) were starting on 400mg, I had no problems on 300mg and I don't really plan on going above that but I think I should still have Inhibitor ready just in case... I no longer have the bloodwork from the cycle unfortunately.

Hello.

What are the e2 blood test values? What dose of testosterone are you using?
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[SalvatoreCorvus]

Last cycle I was on 300mg Enanthate weekly and e2 side effects (sensitive nipples) were starting on 400mg, I had no problems on 300mg and I don't really plan on going above that but I think I should still have Inhibitor ready just in case... I no longer have the bloodwork from the cycle unfortunately.
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▼ Click to expand
Without bloodwork, no one will be able to tell you which medication to take, note the starting dosage. Do blood test today and you will know .
Go do it to find out before you end up with teenage girl nipples.

And then it also depends on how long you've been doing 300-400mg (which is practically the same, going back to 300mg won't fix the problem in my opinion)

 

[Cristy]

My questions: Which should I consider? Anastrozole maybe?
How you use it (dosage and when)?
And Side effects to be known.....
×

blood test before taking medication or adding a 2nd injectable that manages e2 !

There are antiestrogens like anastrozole and exemestane. Anastrozole is better for a beginner but it kills your HDL
Exemestan can kill your e2 easily for several weeks but is better for hdl

Otherwise the injectables that you add to the testosterone like primo, boldo or mast which manage the e2 more or less .
if you use it start with a ratio testo/primo (for example) 2:1
and it is the blood test that determines your ratio
we can't know in advance!
some need a 3:1 ratio others 1:1 and others don't crash their e2 with a 1:2 ratio….

 

[Baugaros]

Last cycle I was on 300mg Enanthate weekly and e2 side effects (sensitive nipples) were starting on 400mg, I had no problems on 300mg and I don't really plan on going above that but I think I should still have Inhibitor ready just in case... I no longer have the bloodwork from the cycle unfortunately.

PePerhaps for the time being, and if the discomfort is only mild, and until the lab tests are available, you could use a SERM like Tamoxifen to minimize the discomfort and prevent tissue formation in the breast. It's not an aromatase inhibitor; it's a selective estrogen receptor modulator.

This way, you'll avoid creating unnecessary hormonal imbalance.

Without lab tests, using AI is like firing missiles without knowing the size of the target...

 

[dr. Doping]

Otherwise the injectables that you add to the testosterone like primo, boldo or mast which manage the e2 more or less .

Masteron does not inhibit aromatase, because unlike primo and EQ, it doesn't have the double bond at position one. It maybe antagonises estrogens at estrogen receptor alpha at high doses (competitive inhibitor). On the other hand, nandrolone seems to upregulate aromatisation (it speeds it up).

 

[Cristy]

Masteron does not inhibit aromatase, because unlike primo and EQ, it doesn't have the double bond at position one. It maybe antagonises estrogens at estrogen receptor alpha at high doses (competitive inhibitor). On the other hand, nandrolone seems to upregulate aromatisation (it speeds it up).

Mast will manage more or less depending on the dose and the person. There is no single dose limit.
As I said, primo boldo mast manage the e2 more or less.
Of course, less for the mast and more for the other 2

 

[dr. Doping]

Mast will manage more or less depending on the dose and the person. There is no single dose limit.
As I said, primo boldo mast manage the e2 more or less.
Of course, less for the mast and more for the other 2

Do you have any bloodwork to share? Mechanistically, we have zero clue why masteron would reduce estradiol, but EQ and primo have the double bond at position 1 (similarly to exemestane and testolactone). I can share a few bloodworks (from about 3 different people) that prove primo reduces estradiol and masteron does not. Best case scenario, masteron just inhibits some activity on estrogen alpha receptors, but that doesn't show on bloodwork.

 

[Cristy]

Do you have any bloodwork to share? Mechanistically, we have zero clue why masteron would reduce estradiol, but EQ and primo have the double bond at position 1 (similarly to exemestane and testolactone). I can share a few bloodworks (from about 3 different people) that prove primo reduces estradiol and masteron does not. Best case scenario, masteron just inhibits some activity on estrogen alpha receptors, but that doesn't show on bloodwork.

I'm just telling you that some people with a high dose of mast have their e2 levels drop. Why, I don't know, on paper as you say it doesn't cut the aromatization, I'll give you some information

 

[dr. Doping]

I'm just telling you that some people with a high dose of mast have their e2 levels drop. Why, I don't know, on paper as you say it doesn't cut the aromatization, I'll give you some information

Maybe they dropped e2 because they got leaner. That's why anecdotes are usually problematic: the variables are not all under control. Masteron is usually used in cutting cycles, so the people you mentioned probably lost bodyfat. This happened to one of my clients.

 

[Cristy]

Maybe they dropped e2 because they got leaner. That's why anecdotes are usually problematic: the variables are not all under control. Masteron is usually used in cutting cycles, so the people you mentioned probably lost bodyfat. This happened to one of my clients.

Yes, I know, that's normal….
I'm talking about the real drop with a high dose, which is the only variable that has changed. And as I said, I don't know how it works because on paper it's not possible. But with illegal products like that, there's the paper and the reaction on the bodies.

 

[unimog]

Maybe they dropped e2 because they got leaner. That's why anecdotes are usually problematic: the variables are not all under control. Masteron is usually used in cutting cycles, so the people you mentioned probably lost bodyfat. This happened to one of my clients.

i agree with you. Masteron is not AI and it actually even might raise e2 because it will binds to shbg and raise free test and consequently potentialize aromatization. But it will feel like anti estrogen because it will also compete with e2 for the estrogen receptors. You actually will feel dry but with high e2. Do you know if there is any dangerous to this? i assume is going to compromise sexual function but does it have a more dangerous side effect?

 

[Lio]

Hi there,
to the initial question of hecarin:
I really don't want to be impolite but it's impossible to answer the question without having basic information such as
A) is this your first cycle or did you have many cacles before
B) what's your acutal bodyweight, bodyhight and bodyfat level

Here's the thing why this data is important:
The dose of any roid you should need ist not depending on fairy tales, experience of other users etc. but directly form the amount of receptors in your body. To make it very simple: If the number of keys you're throwing in is far larger than the number of locks you can be sure it causes problems. That's why a person with f.e. 100kg and 8% bodyfat tolerates and needs higher doses than a person with 80kg and 25% bodyfat - he has far more receptors.

The target always should be to find a dosage with good result without needing pharmaceutical estrogen management (you should have some as a backup if something goes wrong) - it's not the target to use much more than you would need and manage the problems adding estrogen inhibiting products (or prolactin inhibiting products).

 

[dr. Doping]

Do you know if there is any dangerous to this? i assume is going to compromise sexual function but does it have a more dangerous side effect?

Maybe it's even not dangerous, since the estrogen alpha receptor is only "responsible" for feminising effects. Don't know about libido changes, my client who is on 175 test e and 700 mast e had zero complaints

 

[dr. Doping]

The target always should be to find a dosage with good result without needing pharmaceutical estrogen management (you should have some as a backup if something goes wrong) - it's not the target to use much more than you would need and manage the problems adding estrogen inhibiting products (or prolactin inhibiting products).

Yes, to a point, but free testosterone will aromatise even if it does not saturate all androgen receptors, so I don't think the assessment is correct here. It's the androgenic side effects (the non genomic effects) that signify the androgen dose is too high and testosterone will aromatise before that.

 

[Lio]

Yes, to a point, but free testosterone will aromatise even if it does not saturate all androgen receptors, so I don't think the assessment is correct here. It's the androgenic side effects (the non genomic effects) that signify the androgen dose is too high and testosterone will aromatise before that.

Of course, testosterone aromatizes even when receptors are not saturated; otherwise, no normal man would have even a microgram of estrogen, etc., in his body, which would be fatal. However, the key here is to find the right amount of exogenous testosterone so that aromatase doesn't exceed normal levels too much.

To be honest; I'm always very sceptical when somes asks questions concerning "managing estrogen while test-cycle". The reason is quiet simple: Not only too low testosteron f.e. after a cycle can cause problems, too low estrogen levels within the cycle can cause even worse problems.

 

[dr. Doping]

Of course, testosterone aromatizes even when receptors are not saturated; otherwise, no normal man would have even a microgram of estrogen, etc., in his body, which would be fatal. However, the key here is to find the right amount of exogenous testosterone so that aromatase doesn't exceed normal levels too much.

To be honest; I'm always very sceptical when somes asks questions concerning "managing estrogen while test-cycle". The reason is quiet simple: Not only too low testosteron f.e. after a cycle can cause problems, too low estrogen levels within the cycle can cause even worse problems.

I agree on the low e2 being bad, but I do think you can have too much aromatisation on a dose of testosterone, that is not maxxed out (meaning you would still get more anabolism from raising the dose)

 

[METOsin]

what about Arimidyn??

 

[userhiker984567]

My questions: Which should I consider? Anastrozole maybe?
How you use it (dosage and when)?
And Side effects to be known.....

if you are a teenager i would highly recommend to stay away from serms as they close growth plates